GB/T 15670.28-2017 in English

VALID

Toxicological test methods for pesticides registration--Part 28: Combined chronic toxicity/carcinogenicity study

Issued on:2017-07-12
Implemented on:2018-02-01
File Format:PDF
Delivery:Via email within 1~3 business days

Price(USD)： $160.00
$156.00

Standard No:	GB/T 15670.28-2017
Document status:	VALID
Title in English:	Toxicological test methods for pesticides registration--Part 28: Combined chronic toxicity/carcinogenicity study
Title in Chinese:	农药登记毒理学试验方法第28部分：慢性毒性与致癌合并试验
Language:	English
File Format:	Electronic (PDF)
Delivery:	Via email within 1~3 business days
Issued on:	2017-07-12
Implemented on:	2018-02-01
ICS Classification:	65.100-Pesticides and other agrochemicals
Chinese Classification:	B17-Pesticide management and application method
Professional Classification:	GB-National Standard
Related Keywords:	toxicological test methods test data chronic toxicity/carcinogenicity study introduction interpretation carcinogenicity test test evaluate
Related Topics:	toxicology toxicity Carcinogenic Pesticide Registration toxic reaction Toxicology+ Pesticide Toxicity Test Agricultural Sector Consolidation Toxicity verification reaction toxicity Pesticide Registration Toxicology Test Unit Pesticide Registration Test Unit Pesticide Registration Test Unit Toxicity marker 14 Toxicology test chronic toxicity Toxicology test Pesticide Toxicology Test Toxicity standard Pesticide Registration chronic poison Pesticide Registration Toxicology Test Pesticide Toxicology Test Methods Pesticide Registration Toxicology Test What pesticides cause cancer Do pesticides cause cancer? Pesticide Registration Toxicology Test Unit Pesticide Test Registration Unit Toxicology test methods for pesticide registration Toxicity Test Drugs Merging Test and Measurement 28 with cancer Pesticide Registration Toxicology GBT15670.28 GB/T 15670.28-2017 local toxicity test Pesticide 1065 toxicity Toxicology Experimental Methods and Techniques Xu Shuyun’s Pharmacological Experimental Methodology Pharmacopoeia Part 4 Methodology Validation Pharmacological Experimental MethodologyXu Shuyun Pharmacological methodology validation

《GB/T 15670.28-2017农药登记毒理学试验方法第28部分：慢性毒性与致癌合并试验》由326（农业农村部）归口，主管部门为农业农村部。

Introduction

Interpretation of the core content of GB/T15670.28-2017

Chapter	Main content
Scope	Applicable to the combined chronic toxicity and carcinogenicity test for pesticide registration.
Normative references	GB14925 Laboratory animal environment and facilities
Terms and definitions	Clarify key terms such as chronic toxicity and no observed adverse effect level.
Purpose of the test	Evaluate the chronic toxicity and carcinogenic potential of the test substance and determine the NOAEL and LOAEL.

Comparison of standard frameworks and implementation suggestions

Comparative analysis:Compared with GB/T15670-1995, the main changes in this part include structural optimization, content supplementation, and refinement of the requirements for test substances and experimental animals.

Implementation suggestions

Dose setting:At least three dose groups and one control group should be set up, and the high dose should not exceed 1000mg/kg to ensure the validity of the test results.

Application route:Oral, percutaneous or inhalation routes should be selected according to the characteristics of the pesticide, and the standard operating procedures should be strictly followed.

Data analysis:It is recommended to use statistical methods to analyze the test data, especially the calculation of tumor incidence and the selection of evaluation indicators.

More samples: GB 50021-2001(2009) GB 18306-2015 DL/T 368-2010

Sample only — not a preview of GB/T 15670.28-2017

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