WS/T 195-2001 in English

VALID

Diagnositc criteria and principles of management of legionnaires disease

Issued on:2001-07-20
Implemented on:2002-01-01
File Format:PDF
Delivery:Via email within 1~3 business days

Price(USD)： $210.00
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Standard No:	WS/T 195-2001
Document status:	VALID
Title in English:	Diagnositc criteria and principles of management of legionnaires disease
Title in Chinese:	军团病诊断标准及处理原则
Language:	English
File Format:	Electronic (PDF)
Delivery:	Via email within 1~3 business days
Issued on:	2001-07-20
Implemented on:	2002-01-01
Chinese Classification:	C59-
Professional Classification:	WS-Hygiene
Related Keywords:	disease introduction background diagnostic criteria diagnositc criteria diagnostic requirements confirmation requirements epidemiology summer disease
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本标准规定了军团病的诊断标准及处理原则。本标准适用于各级、各类型医疗保舰卫生防疫机构和人员对军团病病例的诊断和处理。

Introduction

Background of Standard Formulation and Technological Evolution

This standard is formulated based on the prevention and control needs of respiratory infectious diseases caused by Legionella pneumophila, and is the first to systematically standardize the diagnostic pathway of Legionnaires' disease in my country. Compared with international standards (such as the CDC 1997 guidelines), the 2001 version adds molecular biological methods such as MPCR detection and Dot-ELISA, reflecting technological iteration.

Core elements of diagnostic criteria

Diagnostic dimensions	Clinical diagnostic requirements	Confirmation requirements
Epidemiology	Summer and autumn seasons + high-risk groups (elderly/smokers/construction workers)	Same as left + environmental isolates
Clinical manifestations	Pneumonia type (fever + pulmonary infiltration) or non-pneumonia type (self-limited)	Same as left + positive specific test
Laboratory examination	Increased erythrocyte sedimentation rate + positive DFA	Positive culture or 4-fold increase in serum antibodies

Comparison of key technical methods

1. Bacterial culture

Using BCYE medium (containing ACES buffer system), the positive rate is only 30-70% but it is the gold standard. The typical colony is frosted glass and Gram staining is negative.

2. Serological testing

Method	Sensitivity	Reporting time	Applicable scenarios
IFA	70-80%	Double serum required (3-8 weeks)	Retrospective diagnosis
DFA	50-70%	2 hours	Rapid screening
ELISA	85%	4 hours	Batch testing

Implementation recommendations

Specimen collection: Prioritize bronchoalveolar lavage fluid (detection rate > 2 times that of sputum specimens)
Treatment monitoring: Be alert to QT interval prolongation when using intravenous erythromycin, and it is recommended to combine with rifampicin
Environmental control: When the Legionella concentration in the cooling tower water is > 1000 CFU/mL, it should be disinfected immediately

More samples: JC/T 2453-2018 GB 18306-2015 JJG 21-2008

Sample only — not a preview of WS/T 195-2001

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