GB/T 34405-2017 in English
VALIDDetermination for migration of acrylamide in household papers-Liquid chromatography-tandem mass spectrometry(LC-MS/MS) method
- Issued on:2017-09-29
- Implemented on:2018-01-01
- File Format:PDF
- Delivery:Via email within 1~3 business days
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《GB/T 34405-2017家用纸制品中丙烯酰胺迁移量的测定 液相色谱-串联质谱法》由TC374(全国质量监管重点产品检验方法标准化技术委员会)归口,主管部门为国家标准化管理委员会。
Introduction
1. Standard Overview
GB/T 34405—2017 "Determination of the Migration of Acrylamide in Household Paper Products by Liquid Chromatography-Tandem Mass Spectrometry" is an important standard for the detection of the migration of acrylamide in household paper products. This standard specifies the method for determining the migration of acrylamide using liquid chromatography-triple quadrupole tandem mass spectrometry (LC-MS/MS) under conditions simulating human contact.
2. Background of Standard Formulation
With the widespread use of household paper products, acrylamide, as a potential harmful substance, has become the focus of public attention. The formulation of this standard aims to ensure consumer health, standardize detection methods, and provide quality assurance for related products.
3. Comparison of standard frameworks
| Dimensions | Standard requirements | Scope of application | Technical requirements |
|---|---|---|---|
| Test objects | Acrylamide migration | Household paper products such as tissue paper, wet wipes, and toilet paper | Liquid chromatography-tandem mass spectrometry (LC-MS/MS) |
| Test conditions | Artificial sweat simulated contact environment | Including the outer coating layer in direct contact with the skin | Electrospray ionization (ESI) and multiple reaction monitoring (MRM) mode |
| Data processing | Combination of quantitative analysis and qualitative analysis | Applicable to batch testing | Standard working curve method |
4. Implementation suggestions
Implementation suggestions:
- The laboratory should be equipped with Liquid chromatography-tandem mass spectrometry (LC-MS/MS) and its auxiliary equipment to ensure that the standard requirements are met.
- Operators need to receive professional training and be familiar with the determination process and data analysis methods of acrylamide migration.
- It is recommended to calibrate the instrument regularly and conduct blank tests and repeatability tests to ensure data accuracy.
- In actual applications, other detection methods (such as high performance liquid chromatography) can be combined to verify the results and improve detection efficiency.

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