WS/T 595-2018 in English
VALIDGuidelines on the interventions for donation related vasovagal reaction
- Issued on:2018-02-05
- Implemented on:2018-07-01
- File Format:PDF
- Delivery:Via email within 1~3 business days
Price(USD)：
$570.00
$553.00
$553.00
本标准规定了献血相关血管迷走神经反应（donation related vasovagal reaction，DRVR）易发人群的识别、预防和处置措施、人员和设施要求。
本标准适用于DRVR的预防和处置。
Introduction
Interpretation of the core content of the standard
DRVR (Donation-Related Vasovagal Reaction): refers to the physiological reaction caused by vagus nerve excitement during blood donation, characterized by a decrease in blood pressure and a slowing of heart rate. In severe cases, it can lead to syncope.
Comparison of key technical requirements
| Control dimensions | Whole blood donation | Apheresis blood donation |
|---|---|---|
| Maximum blood collection volume | ≤15% of blood volume (≤13% for susceptible populations) | Extracorporeal circulation volume≤15% of blood volume |
| Special populations | Female first-time blood donors aged <23 years should be carefully selected to donate 400mL | BMI≥26 should be calculated using the Holme formula |
| Preventive measures | AMT muscle training + salt-containing fluid supplementation | Intravenous fluid replacement + real-time monitoring |
Detailed explanation of implementation points
1. Identification of vulnerable groups
- High-risk characteristics: Age <23 years, female, first-time blood donor, blood volume <3300mL
- Screening tool: A standardized questionnaire is used to assess fear of blood donation (Sample question: "Are you afraid of having blood drawn from your arm?")
2. Accurate calculation of blood volume
Nadler formula (BMI <26):
Female BV=(0.3561×H³+0.03308×W+0.1833)×1000
For males, BV = (0.3669 × H³ + 0.03219 × W + 0.6041) × 1000.
Female BV=(0.3561×H³+0.03308×W+0.1833)×1000
For males, BV = (0.3669 × H³ + 0.03219 × W + 0.6041) × 1000.
Note: H is height (m), W is weight (kg), and BV is in mL.
3. Preventive Intervention Measures
Application Case: During a blood donation activity at a certain university, a 19-year-old female first-time blood donor with a BMI of 22:
- Blood volume calculated using the Nadler method was 2980 mL
- Blood collection volume was controlled at 300 mL (accounting for 10.1%)
- Drink 500 mL of saline solution 20 minutes before blood collection
- Perform AMT muscle training
Background of Standard Evolution
This standard is developed based on the WS/T 551 Guidelines for the Classification of Adverse Reactions. Its major technical breakthroughs include:
- For the first time, the volume control thresholds for different blood donation forms are clarified
- A quantitative blood volume calculation method is introduced
- A hierarchical prevention system is established (basic prevention → enhanced prevention)
Solutions to Common Problems
| Problem phenomenon | Handling process |
|---|---|
| Fainting at the blood donation site | Immediately stop blood collection → Place the patient in a Trendelenburg position → Press acupoints → Monitor vital signs |
| Dizziness after leaving the site | Instruct the patient to squat immediately → Rest in a supine position → AMT training → Follow-up at the blood bank |
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