GB/T 36942-2018 in English

GB/T 36942—2018 Standard Overview

This standard specifies the determination method of 10 alkaloids (scorine, strychnine, aconitine, etc.) in cosmetics, using liquid chromatography tandem mass spectrometry (LC-MS/MS), and is applicable to creams, lotions and aqueous cosmetics.

Background of Standard Formulation

As the safety of banned substances in cosmetics has received increasing attention, the formulation of this standard fills the gap in my country's cosmetics testing technology. The presence and content of these harmful substances are determined by scientific methods to ensure the safety of consumers.

Technology Evolution Analysis

LC-MS/MS technology combines the advantages of high-performance liquid chromatography separation and mass spectrometry detection, and can achieve high-sensitivity and high-specificity analysis. Based on this technology, this standard optimizes the sample pretreatment process and instrument parameter settings, significantly improving the detection efficiency.

Comparative analysis of standard framework

Compared with similar international standards, this standard has higher applicability and accuracy in sample pretreatment, instrument parameter setting and data analysis. The following is a comparison of standard frameworks from multiple dimensions:

Implementation Recommendations

To ensure the effective implementation of the standards, it is recommended that:

• The laboratory should be equipped with a liquid chromatography tandem mass spectrometer that meets the requirements;
• Operators should undergo professional training;
• A sound quality control system should be established;
• Regularly calibrate the instrument to ensure the accuracy of the test results.