WS/T 237-2016 in English

VALID

Diagnosis of lymphogranuloma venereum

Issued on:2016-11-29
Implemented on:2017-06-01
File Format:PDF
Delivery:Via email within 1~3 business days

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Standard No:	WS/T 237-2016
Document status:	VALID
Title in English:	Diagnosis of lymphogranuloma venereum
Title in Chinese:	性病性淋巴肉芽肿诊断
Language:	English
File Format:	Electronic (PDF)
Delivery:	Via email within 1~3 business days
Issued on:	2016-11-29
Implemented on:	2017-06-01
Superseding:	WS 237-2003 Diagnostic criteria and principles of management of lymphogranuloma venereum
ICS Classification:	11.020-Medical Sciences and health care facilities in general
Chinese Classification:	C59-
Professional Classification:	WS-Hygiene
Related Keywords:	grading secondary diagnosis differential diagnosis laboratory methods histopathological examination newly added nucleic acid detection lymphogranuloma venereum introduction background acid detection technology
Related Topics:	lymph box buds shower chronic lymphatic chronic lymphatic venereal disease Lymphatic Granulomatous Lymphatic Granuloma negative and positive super gonorrhea Jimsa -bar positive and negative Foreign Pathological Diagnosis Lymphatic diagnostic sensitivity Pathological diagnosis of dermatopathic lymphadenitis Hydrops fetalis diagnosis Kikuchi disease diagnosis

本标准规定了性病性淋巴肉芽肿的诊断原则、诊断依据、诊断分类和鉴别诊断。
本标准适用于全国各级各类医疗卫生机构及其医务人员对性病性淋巴肉芽肿的诊断。

Introduction

Background of Standard Revision and Major Changes

Comparison Dimensions	WS 237-2003	WS/T 237-2016
Nature of the Standard	Mandatory	Recommended
Diagnostic Grading	Undefined Grading	Secondary Diagnosis (Suspected/Confirmed)
Laboratory Methods	Histopathological Examination	Newly Added Nucleic Acid Detection and Typing Identification

Analysis of core diagnostic elements

1. Clinical manifestations and stages

Early stage (3-30 days): Characteristic primary sores are characterized by small painless ulcers, which are more common in the genitals and perianal areas. Those with rectal infection may have mucus and blood in the stool.

Mid-stage (2-6 weeks): Typical buccaneerosis with groove sign, systemic symptoms such as fever, joint pain, etc.

Late stage (after 2 years): Irreversible damage such as rectal stenosis and fistula formation.

2. Laboratory examination techniques

Detection method	Sensitivity	Specificity	Clinical significance
Microimmunofluorescence test	Moderate	High	Antibody titer ≥1:512 has diagnostic value
Cell culture	About 50%	100%	Need to be combined with molecular typing to confirm L type
Nucleic acid detection	＞90%	＞95%	Require omp1 genotyping

Implementation recommendations

For suspected cases, MIF serology and nucleic acid testing should be combined to improve the detection rate
Ultrasonic pretreatment is recommended for rectal specimens to reduce contamination
Culture-positive specimens must be identified for L1-L3 serotypes
Pay attention to differential diagnosis from syphilis chancre and genital herpes

Technology evolution analysis

The 2016 version of the standard reflects three major technological advances: ①Nucleic acid detection technology replaces traditional pathological examination; ②Optimization of the diagnostic grading system; ③Deletion of the treatment part to achieve separation of diagnosis and treatment. It is recommended that laboratories establish an omp1 gene sequencing platform to improve typing capabilities.

More samples: JC/T 2453-2018 YD/T 3934-2021 JGJ 94-2008

Sample only — not a preview of WS/T 237-2016