WS/T 623-2018 in English
VALIDTransfusion of whole blood and blood components
- Issued on:2018-09-26
- Implemented on:2019-04-01
- File Format:PDF
- Delivery:Via email within 1~3 business days
$272.00
本标准规定了全血和成分血的适应证、输注剂量和使用方法。
本标准适用于医疗机构开展临床输血治疗的全过程。
Introduction
Analysis of the Standard's Core Content
Background and Technological Evolution
This standard was developed based on the Blood Donation Law of the People's Republic of China and the Administrative Measures for Clinical Blood Use in Medical Institutions and was jointly drafted by eight authoritative institutions, including the Institute of Transfusion Medicine, Chinese Academy of Medical Sciences. It reflects the significant shift in transfusion medicine in my country from whole blood transfusion to component transfusion, and embodies the application of the concept of precision medicine in the field of blood transfusion.
Comparison of clinical applications of blood preparations
| Preparation type | Key ingredients | Main indications | Special contraindications |
|---|---|---|---|
| Suspended red blood cells | Hct 0.50-0.65 | Acute and chronic anemia | Hb＞100g/L No indication |
| Apheresis platelets | ≥2.5×1011/therapeutic dose | Thrombocytopenic bleeding | Use TTP with caution |
| Fresh frozen plasma | All coagulation factors | Multifactor deficiency | Use with caution if INR < 1.7 |
Key technical points
Red blood cell transfusion decision matrix
- Critical value: Patients with active bleeding are not limited by the Hb threshold
- Dose calculation: 1U red blood cells ≈ 5g/L increase in adult Hb (60kg body weight)
- Special populations: Infants and young children, 10-15mL/kg can increase Hb by 20-30g/L
Platelet transfusion standards
Typical case: A patient after cardiac surgery had a platelet count of 50×109/L with oozing blood. single-donor platelets were preferred over platelet concentrates to reduce the risk of alloimmunization.
Clinical implementation recommendations
Four elements of safe transfusion
- Strictly follow the ABO/Rh isotype principle
- Initial slow infusion for 15 minutes to observe reactions
- Use a dedicated blood transfusion device (170-200μm filter)
- Complete transfusion within 4 hours of release
Special handling requirements
Immunocompromised patients, blood transfusions between relatives, and granulocyte preparations must be irradiated (25-50Gy) to prevent TA-GVHD.
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