SN/T 5111-2019 in English

Technical background of the standard

This standard is formulated to address the residual risk of Praziquantel in food animals and feed. As a broad-spectrum antiparasitic drug, its residues may threaten human health through the food chain. The General Administration of Customs issued this standard in 2019, filling the gap in my country's detection technology in this field.

Core parameters of the method

Key Operation Flow

Optimization of mass spectrometry parameters

The ESI+ ion source was used to monitor the parent ions m/z 313→203 (quantitative ion) and 313→83 (qualitative ion), with collision energies of 14V and 24V, respectively. In actual applications, it was found that the best response was obtained when the source temperature was 550℃.

Implementation suggestions

1. The laboratory needs to regularly verify the sensitivity of the mass spectrometer to ensure that it meets the requirements for low-concentration detection
2. It is recommended to verify the extraction efficiency of different matrix samples, and special attention should be paid to lipid interference in feed samples
3. The standard solution should be prepared using a ≥98% purity praziquantel standard (CAS: 55268-74-1)