SN/T 5449-2022 in English

Interpretation of the core content of the standard

This standard establishes an analytical method for the determination of chlorpyrifos residues in plant-derived foods by liquid chromatography-tandem mass spectrometry. Chlorpyrifos is converted into 2,4-dinitro-6-(1-methylheptyl)phenol (2,4-DNOP) through alkaline hydrolysis and then detected. The limit of quantification is 0.01 mg/kg.

Analysis of key technical points

Method Validation Data

Implementation recommendations

1. Key points for quality control: Each batch of samples needs to undergo matrix matching standard curve and blank spike experiments simultaneously
2. Equipment calibration: The liquid chromatography system needs to be checked for retention time drift daily (≤±2.5%)
3. Method expansion: The scope of application can be extended to other similar matrices through verification

Background of standard evolution

This standard fills the gap in the detection standard for mite in my country's exported food. The technical route refers to the EU SANTE/12682/2019 guidelines. The detection sensitivity is 10 times higher than that of the traditional GC method, which meets the increasingly stringent pesticide residue limit requirements in international trade.